1R5H
Crystal Structure of MetAP2 complexed with A320282
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Methionine aminopeptidase 2 | polymer | 369 | 41370.0 | 1 | UniProt (P50579) Pfam (PF00557) In PDB | Homo sapiens (human) | MetAP 2, Peptidase M 2, Initiation factor 2 associated 67 kDa glycoprotein, p67, p67eIF2 |
| 2 | A | MANGANESE (II) ION | non-polymer | 54.9 | 2 | Chemie (MN) | |||
| 3 | A | N'-(2S,3R)-3-AMINO-4-CYCLOHEXYL-2-HYDROXY-BUTANO-N-(4-METHYLPHENYL)HYDRAZIDE | non-polymer | 305.4 | 1 | Chemie (AO2) | |||
| 4 | water | water | 18.0 | 348 | Chemie (HOH) |
Sequence modifications
A: 110 - 478 (UniProt: P50579)
| PDB | External Database | Details |
|---|---|---|
| Ile 347 | Val 347 | CONFLICT |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 41370.0 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 415.3 | |
| All* | Total formula weight | 41785.3 |
