1R35

MURINE INDUCIBLE NITRIC OXIDE SYNTHASE OXYGENASE DIMER, TETRAHYDROBIOPTERIN AND 4R-FLUORO-N6-ETHANIMIDOYL-L-LYSINE

Summary for 1R35

Entry DOI	10.2210/pdb1r35/pdb
Descriptor	Nitric oxide synthase, inducible, SULFATE ION, PROTOPORPHYRIN IX CONTAINING FE, ... (6 entities in total)
Functional Keywords	nitric oxide monooxygenase, heme, dimer, intermediate, pterin, h4b, tetrahydrobiopterin, oxidoreductase
Biological source	Mus musculus (house mouse)
Total number of polymer chains	2
Total formula weight	102463.90
Authors	Shieh, H.S.,Stevens, A.M.,Stallings, W.C. (deposition date: 2003-09-30, release date: 2004-10-05, Last modification date: 2023-08-23)
Primary citation	Hallinan, E.A.,Kramer, S.W.,Houdek, S.C.,Moore, W.M.,Jerome, G.M.,Spangler, D.P.,Stevens, A.M.,Shieh, H.S.,Manning, P.T.,Pitzele, B.S. 4-Fluorinated L-lysine analogs as selective i-NOS inhibitors: methodology for introducing fluorine into the lysine side chain. Org.Biomol.Chem., 1:3527-3534, 2003 Cited by PubMed: 14599013 DOI: 10.1039/b307563j PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.3 Å)

Structure validation