1R35

MURINE INDUCIBLE NITRIC OXIDE SYNTHASE OXYGENASE DIMER, TETRAHYDROBIOPTERIN AND 4R-FLUORO-N6-ETHANIMIDOYL-L-LYSINE

1R35 の概要

• エントリーDOI: 10.2210/pdb1r35/pdb
• 分子名称: Nitric oxide synthase, inducible, SULFATE ION, PROTOPORPHYRIN IX CONTAINING FE, ... (6 entities in total)
• 機能のキーワード: nitric oxide monooxygenase, heme, dimer, intermediate, pterin, h4b, tetrahydrobiopterin, oxidoreductase
• 由来する生物種: Mus musculus (house mouse)
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 102463.90

構造登録者

Shieh, H.S.,Stevens, A.M.,Stallings, W.C. (登録日: 2003-09-30, 公開日: 2004-10-05, 最終更新日: 2023-08-23)

• 主引用文献: Hallinan, E.A.,Kramer, S.W.,Houdek, S.C.,Moore, W.M.,Jerome, G.M.,Spangler, D.P.,Stevens, A.M.,Shieh, H.S.,Manning, P.T.,Pitzele, B.S.; 4-Fluorinated L-lysine analogs as selective i-NOS inhibitors: methodology for introducing fluorine into the lysine side chain.; Org.Biomol.Chem., 1:3527-3534, 2003; PubMed: 14599013; DOI: 10.1039/b307563j

実験手法

X-RAY DIFFRACTION (2.3 Å)