1QX4
Structrue of S127P mutant of cytochrome b5 reductase
Summary for 1QX4
Entry DOI | 10.2210/pdb1qx4/pdb |
Related | 1I7P 1IB0 |
Descriptor | NADH-cytochrome b5 reductase, FLAVIN-ADENINE DINUCLEOTIDE (3 entities in total) |
Functional Keywords | methemoglobinemia, flavin flexibility, oxidoreductase |
Biological source | Rattus norvegicus (Norway rat) |
Cellular location | Isoform 1: Endoplasmic reticulum membrane; Lipid-anchor; Cytoplasmic side. Isoform 3: Cytoplasm: P20070 |
Total number of polymer chains | 2 |
Total formula weight | 64221.53 |
Authors | Bewley, M.C.,Davis, C.A.,Marohnic, C.C.,Taormina, D.,Barber, M.J. (deposition date: 2003-09-04, release date: 2004-09-14, Last modification date: 2023-08-23) |
Primary citation | Bewley, M.C.,Davis, C.A.,Marohnic, C.C.,Taormina, D.,Barber, M.J. The structure of the S127P mutant of cytochrome b5 reductase that causes methemoglobinemia shows the AMP moiety of the flavin occupying the substrate binding site Biochemistry, 42:13145-13151, 2003 Cited by PubMed: 14609324DOI: 10.1021/bi034915c PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.8 Å) |
Structure validation
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