1QTN
CRYSTAL STRUCTURE OF THE COMPLEX OF CASPASE-8 WITH THE TETRAPEPTIDE INHIBITOR ACE-IETD-ALDEHYDE
Summary for 1QTN
Entry DOI | 10.2210/pdb1qtn/pdb |
Related PRD ID | PRD_000301 |
Descriptor | CASPASE-8, ACETYL-ILE-GLU-THR-ASP-ALDEHYDE, DITHIANE DIOL, ... (5 entities in total) |
Functional Keywords | apoptosis, dithiane-diol, caspase, cysteine-protease, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
Biological source | Homo sapiens (human) More |
Cellular location | Cytoplasm: Q14790 Q14790 |
Total number of polymer chains | 3 |
Total formula weight | 30334.49 |
Authors | Watt, W.,Watenpaugh, K.D. (deposition date: 1999-06-28, release date: 2000-09-20, Last modification date: 2023-11-15) |
Primary citation | Watt, W.,Koeplinger, K.A.,Mildner, A.M.,Heinrikson, R.L.,Tomasselli, A.G.,Watenpaugh, K.D. The atomic-resolution structure of human caspase-8, a key activator of apoptosis. Structure Fold.Des., 7:1135-1143, 1999 Cited by PubMed: 10508785DOI: 10.1016/S0969-2126(99)80180-4 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.2 Å) |
Structure validation
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