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1QIC

CRYSTAL STRUCTURE OF STROMELYSIN CATALYTIC DOMAIN

Summary for 1QIC
Entry DOI10.2210/pdb1qic/pdb
DescriptorPROTEIN (STROMELYSIN-1), ZINC ION, CALCIUM ION, ... (4 entities in total)
Functional Keywordsinhibitor, matrixin, matrix metalloproteinase-3 (mmp-3), stromelysin-1, metzincin, hydrolase
Biological sourceHomo sapiens (human)
Cellular locationSecreted, extracellular space, extracellular matrix : P08254
Total number of polymer chains4
Total formula weight73336.62
Authors
Williams, M.G.,Ye, Q.-Z.,Molina, F.,Johnson, L.L.,Ortwine, D.F.,Pavlovsky, A.G.,Rubin, J.R.,Skeean, R.W.,White, A.D.,Blundell, T.L.,Humblet, C.,Hupe, D.J.,Dhanaraj, V. (deposition date: 1999-06-11, release date: 2003-02-11, Last modification date: 2023-12-27)
Primary citationPavlovsky, A.G.,Williams, M.G.,Ye, Q.-Z.,Ortwine, D.F.,Purchase II, C.F.,White, A.D.,Dhanaraj, V.,Roth, B.D.,Johnson, L.L.,Hupe, D.J.,Humblet, C.,Blundell, T.L.
X-ray structure of human stromelysin catalytic domain complexed with nonpeptide inhibitors: implications for inhibitor selectivity
Protein Sci., 8:1455-1462, 1999
Cited by
PubMed: 10422833
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2 Å)
Structure validation

217705

건을2024-03-27부터공개중

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