1QG6

CRYSTAL STRUCTURE OF E. COLI ENOYL ACYL CARRIER PROTEIN REDUCTASE IN COMPLEX WITH NAD AND TRICLOSAN

Summary for 1QG6

DescriptorPROTEIN (ENOYL-[ACYL-CARRIER PROTEIN] REDUCTASE), NICOTINAMIDE-ADENINE-DINUCLEOTIDE, TRICLOSAN, ... (4 entities in total)
Functional Keywordsfatty acid synthesis, antibacterial, oxidoreductase
Biological sourceEscherichia coli
Total number of polymer chains4
Total molecular weight114858.79
Authors
Rowsell, S.,Pauptit, R.A. (deposition date: 1999-04-20, release date: 1999-09-21, Last modification date: 2011-07-13)
Primary citation
Ward, W.H.,Holdgate, G.A.,Rowsell, S.,McLean, E.G.,Pauptit, R.A.,Clayton, E.,Nichols, W.W.,Colls, J.G.,Minshull, C.A.,Jude, D.A.,Mistry, A.,Timms, D.,Camble, R.,Hales, N.J.,Britton, C.J.,Taylor, I.W.
Kinetic and structural characteristics of the inhibition of enoyl (acyl carrier protein) reductase by triclosan.
Biochemistry, 38:12514-12525, 1999
PubMed: 10493822 (PDB entries with the same primary citation)
DOI: 10.1021/bi9907779
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (1.9 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.204403.6%1.8%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution