1QBG
CRYSTAL STRUCTURE OF HUMAN DT-DIAPHORASE (NAD(P)H OXIDOREDUCTASE)
Summary for 1QBG
Entry DOI | 10.2210/pdb1qbg/pdb |
Descriptor | NAD(P)H DEHYDROGENASE [QUINONE] 1, FLAVIN-ADENINE DINUCLEOTIDE (2 entities in total) |
Functional Keywords | quinone, fad, oxidoreductase, dt-diaphorase |
Biological source | Homo sapiens (human) |
Cellular location | Cytoplasm: P15559 |
Total number of polymer chains | 4 |
Total formula weight | 126019.66 |
Authors | Skelly, J.V.,Sanderson, M.R.,Suter, D.A.,Baumann, U.,Gregory, D.S.,Bennett, M.,Hobbs, S.M.,Neidle, S. (deposition date: 1999-04-20, release date: 2000-04-24, Last modification date: 2024-02-14) |
Primary citation | Skelly, J.V.,Sanderson, M.R.,Suter, D.A.,Baumann, U.,Read, M.A.,Gregory, D.S.,Bennett, M.,Hobbs, S.M.,Neidle, S. Crystal structure of human DT-diaphorase: a model for interaction with the cytotoxic prodrug 5-(aziridin-1-yl)-2,4-dinitrobenzamide (CB1954). J.Med.Chem., 42:4325-4330, 1999 Cited by PubMed: 10543876DOI: 10.1021/jm991060m PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.3 Å) |
Structure validation
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