1QA7

CRYSTAL COMPLEX OF THE 3C PROTEINASE FROM HEPATITIS A VIRUS WITH ITS INHIBITOR AND IMPLICATIONS FOR THE POLYPROTEIN PROCESSING IN HAV

1QA7 の概要

• エントリーDOI: 10.2210/pdb1qa7/pdb
• 分子名称: HAV 3C PROTEINASE, N-(iodoacetyl)-L-valyl-L-phenylalaninamide, DIMETHYL SULFOXIDE, ... (5 entities in total)
• 機能のキーワード: chymotrypsin-like cysteine proteinase viral protease p'-site inhibitor, hydrolase, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
• 由来する生物種: Hepatitis A virus
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 97209.18

構造登録者

Bergmann, E.M.,Cherney, M.M.,Mckendrick, J.,Vederas, J.C.,James, M.N.G. (登録日: 1999-04-15, 公開日: 1999-04-20, 最終更新日: 2023-08-16)

• 主引用文献: Bergmann, E.M.,Cherney, M.M.,Mckendrick, J.,Frormann, S.,Luo, C.,Malcolm, B.A.,Vederas, J.C.,James, M.N.; Crystal structure of an inhibitor complex of the 3C proteinase from hepatitis A virus (HAV) and implications for the polyprotein processing in HAV.; Virology, 265:153-163, 1999; PubMed: 10603326; DOI: 10.1006/viro.1999.9968

実験手法

X-RAY DIFFRACTION (1.9 Å)