1Q66
CRYSTAL STRUCTURE OF TGT IN COMPLEX WITH 2-AMINO-6-AMINOMETHYL-8-phenylsulfanylmethyl-3H-QUINAZOLIN-4-ONE crystallized at pH 5.5
Summary for 1Q66
Entry DOI | 10.2210/pdb1q66/pdb |
Related | 1pud 1Q4W 1Q63 1Q65 |
Descriptor | Queuine tRNA-ribosyltransferase, ZINC ION, 2-AMINO-6-AMINOMETHYL-8-PHENYLSULFANYLMETHYL-3H-QUINAZOLIN-4-ONE, ... (4 entities in total) |
Functional Keywords | transferase |
Biological source | Zymomonas mobilis |
Total number of polymer chains | 1 |
Total formula weight | 43303.50 |
Authors | Brenk, R.,Meyer, E.,Reuter, K.,Stubbs, M.T.,Garcia, G.A.,Klebe, G. (deposition date: 2003-08-12, release date: 2004-04-13, Last modification date: 2023-08-16) |
Primary citation | Brenk, R.,Meyer, E.,Reuter, K.,Stubbs, M.T.,Garcia, G.A.,Diederich, F.,Klebe, G. Crystallographic Study of Inhibitors of tRNA-guanine Transglycosylase Suggests a New Structure-based Pharmacophore for Virtual Screening. J.Mol.Biol., 338:55-75, 2004 Cited by PubMed: 15050823DOI: 10.1016/j.jmb.2004.02.019 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.75 Å) |
Structure validation
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