1Q5M

Binary complex of rabbit 20alpha-hydroxysteroid dehydrogenase with NADPH

Summary for 1Q5M

• Entry DOI: 10.2210/pdb1q5m/pdb
• Related: 1Q13
• Descriptor: Prostaglandin-E2 9-reductase, SULFATE ION, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... (4 entities in total)
• Functional Keywords: nadph, hsd, hydroxysteroid dehydrogenase, aldo-keto reductase, oxidoreductase
• Biological source: Oryctolagus cuniculus (rabbit)
• Cellular location: Cytoplasm: P80508
• Total number of polymer chains: 2
• Total formula weight: 74861.05

Authors

Couture, J.F.,Legrand, P.,Cantin, L.,Labrie, F.,Luu-The, V.,Breton, R. (deposition date: 2003-08-08, release date: 2004-05-18, Last modification date: 2024-02-14)

• Primary citation: Couture, J.F.,Legrand, P.,Cantin, L.,Labrie, F.,Luu-The, V.,Breton, R.; Loop Relaxation, A Mechanism that Explains the Reduced Specificity of Rabbit 20alpha-Hydroxysteroid Dehydrogenase, A Member of the Aldo-Keto Reductase Superfamily.; J.Mol.Biol., 339:89-102, 2004; PubMed: 15123423; DOI: 10.1016/j.jmb.2004.03.035

Experimental method

X-RAY DIFFRACTION (1.32 Å)