1PZT

CRYSTAL STRUCTURE OF W314A-BETA-1,4-GALACTOSYLTRANSFERASE (B4GAL-T1) CATALYTIC DOMAIN WITHOUT SUBSTRATE

Summary for 1PZT

Entry DOI	10.2210/pdb1pzt/pdb
Related	1FGX 1O0R
Descriptor	Beta-1,4-galactosyltransferase 1, SULFATE ION (3 entities in total)
Functional Keywords	beta1, 4-galactosyltransferase-i tryptophan mutant, flexible loop conformation, protease digestion, substrate binding, catalytic mechanism, transferase
Biological source	Bos taurus (cattle)
Cellular location	Isoform Long: Golgi apparatus, Golgi stack membrane; Single-pass type II membrane protein. Isoform Short: Golgi apparatus, Golgi stack membrane; Single-pass type II membrane protein. Processed beta-1,4-galactosyltransferase 1: Secreted: P08037
Total number of polymer chains	1
Total formula weight	32830.51
Authors	Ramasamy, V.,Ramakrishnan, B.,Boeggeman, E.,Qasba, P.K. (deposition date: 2003-07-14, release date: 2003-09-16, Last modification date: 2023-08-16)
Primary citation	Ramasamy, V.,Ramakrishnan, B.,Boeggeman, E.,Qasba, P.K. The role of tryptophan 314 in the conformational changes of beta1,4-galactosyltransferase-I J.Mol.Biol., 331:1065-1076, 2003 Cited by PubMed: 12927542 DOI: 10.1016/S0022-2836(03)00790-3 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.92 Å)

Structure validation