1PYE
Crystal structure of CDK2 with inhibitor
Summary for 1PYE
Entry DOI | 10.2210/pdb1pye/pdb |
Related | 1PY5 |
Descriptor | Cell division protein kinase 2, [2-AMINO-6-(2,6-DIFLUORO-BENZOYL)-IMIDAZO[1,2-A]PYRIDIN-3-YL]-PHENYL-METHANONE (3 entities in total) |
Functional Keywords | cdk, cyclin-dependent kinase 2, transferase |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 1 |
Total formula weight | 34353.83 |
Authors | Zhang, F.,Hamdouchi, C. (deposition date: 2003-07-08, release date: 2004-07-13, Last modification date: 2024-02-14) |
Primary citation | Hamdouchi, C.,Keyser, H.,Collins, E.,Jaramillo, C.,De Diego, J.E.,Spencer, C.D.,Dempsey, J.A.,Anderson, B.D.,Leggett, T.,Stamm, N.B.,Schultz, R.M.,Watkins, S.A.,Cocke, K.,Lemke, S.,Burke, T.F.,Beckmann, R.P.,Dixon, J.T.,Gurganus, T.M.,Rankl, N.B.,Houck, K.A.,Zhang, F.,Vieth, M.,Espinosa, J.,Timm, D.E.,Campbell, R.M.,Patel, B.K.,Brooks, H.B. The discovery of a new structural class of cyclin-dependent kinase inhibitors, aminoimidazo[1,2-a]pyridines. MOL.CANCER THER., 3:1-9, 2004 Cited by PubMed: 14749470PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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