1PT9
Crystal Structure Analysis of the DIII Component of Transhydrogenase with a Thio-Nicotinamide Nucleotide Analogue
Summary for 1PT9
Entry DOI | 10.2210/pdb1pt9/pdb |
Related | 1PTJ |
Descriptor | NAD(P) transhydrogenase, mitochondrial, SULFATE ION, 7-THIONICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... (5 entities in total) |
Functional Keywords | transhydrogenase, thio-nicotinamide, mitochondria, proton translocation, oxidoreductase |
Biological source | Homo sapiens (human) |
Cellular location | Mitochondrion inner membrane ; Multi-pass membrane protein ; Matrix side : Q13423 |
Total number of polymer chains | 2 |
Total formula weight | 46458.56 |
Authors | Singh, A.,Venning, J.D.,Quirk, P.G.,van Boxel, G.I.,Rodrigues, D.J.,White, S.A.,Jackson, J.B. (deposition date: 2003-06-23, release date: 2003-10-07, Last modification date: 2023-08-16) |
Primary citation | Singh, A.,Venning, J.D.,Quirk, P.G.,Van Boxel, G.I.,Rodrigues, D.J.,White, S.A.,Jackson, J.B. Interactions between transhydrogenase and thio-nicotinamide analogues of NAD(H) and NADP(H) underline the importance of nucleotide conformational changes in coupling to proton translocation J.Biol.Chem., 278:33208-33216, 2003 Cited by PubMed: 12791694DOI: 10.1074/jbc.M303061200 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.42 Å) |
Structure validation
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