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1PSA

STRUCTURE OF A PEPSIN(SLASH)RENIN INHIBITOR COMPLEX REVEALS A NOVEL CRYSTAL PACKING INDUCED BY MINOR CHEMICAL ALTERATIONS IN THE INHIBITOR

Summary for 1PSA
Entry DOI10.2210/pdb1psa/pdb
Related PRD IDPRD_000378
DescriptorPEPSIN A, N-(ethoxycarbonyl)-L-leucyl-N-[(1R,2S,3S)-1-(cyclohexylmethyl)-2,3-dihydroxy-5-methylhexyl]-L-leucinamide (3 entities in total)
Functional Keywordsacid proteinase, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
Biological sourceSus scrofa (pig)
Cellular locationSecreted: P00791
Total number of polymer chains2
Total formula weight70110.54
Authors
Chen, L.,Abad-Zapatero, C. (deposition date: 1991-10-22, release date: 1994-01-31, Last modification date: 2017-11-29)
Primary citationChen, L.,Erickson, J.W.,Rydel, T.J.,Park, C.H.,Neidhart, D.,Luly, J.,Abad-Zapatero, C.
Structure of a pepsin/renin inhibitor complex reveals a novel crystal packing induced by minor chemical alterations in the inhibitor.
Acta Crystallogr.,Sect.B, 48:476-488, 1992
Cited by
PubMed: 1418819
DOI: 10.1107/S0108768192001939
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.9 Å)
Structure validation

217705

數據於2024-03-27公開中

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