1PSA

STRUCTURE OF A PEPSIN(SLASH)RENIN INHIBITOR COMPLEX REVEALS A NOVEL CRYSTAL PACKING INDUCED BY MINOR CHEMICAL ALTERATIONS IN THE INHIBITOR

1PSA の概要

• エントリーDOI: 10.2210/pdb1psa/pdb
• 関連するBIRD辞書のPRD_ID: PRD_000378
• 分子名称: PEPSIN A, N-(ethoxycarbonyl)-L-leucyl-N-[(1R,2S,3S)-1-(cyclohexylmethyl)-2,3-dihydroxy-5-methylhexyl]-L-leucinamide (3 entities in total)
• 機能のキーワード: acid proteinase, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
• 由来する生物種: Sus scrofa (pig)
• 細胞内の位置: Secreted: P00791
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 70110.54

構造登録者

Chen, L.,Abad-Zapatero, C. (登録日: 1991-10-22, 公開日: 1994-01-31, 最終更新日: 2017-11-29)

• 主引用文献: Chen, L.,Erickson, J.W.,Rydel, T.J.,Park, C.H.,Neidhart, D.,Luly, J.,Abad-Zapatero, C.; Structure of a pepsin/renin inhibitor complex reveals a novel crystal packing induced by minor chemical alterations in the inhibitor.; Acta Crystallogr.,Sect.B, 48:476-488, 1992; PubMed: 1418819; DOI: 10.1107/S0108768192001939

実験手法

X-RAY DIFFRACTION (2.9 Å)