1PRM

TWO BINDING ORIENTATIONS FOR PEPTIDES TO SRC SH3 DOMAIN: DEVELOPMENT OF A GENERAL MODEL FOR SH3-LIGAND INTERACTIONS

1PRM の概要

• エントリーDOI: 10.2210/pdb1prm/pdb
• 分子名称: C-SRC TYROSINE KINASE SH3 DOMAIN, PROLINE-RICH LIGAND PLR1 (AFAPPLPRR) (2 entities in total)
• 機能のキーワード: complex (signal transduction-peptide), complex (signal transduction-peptide) complex, complex (signal transduction/peptide)
• 由来する生物種: Gallus gallus (chicken)
• 細胞内の位置: Cell membrane (By similarity): P00523
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 8029.88

構造登録者

Feng, S.,Chen, J.K.,Yu, H.,Simon, J.A.,Schreiber, S.L. (登録日: 1994-10-10, 公開日: 1995-02-07, 最終更新日: 2022-03-02)

• 主引用文献: Feng, S.,Chen, J.K.,Yu, H.,Simon, J.A.,Schreiber, S.L.; Two binding orientations for peptides to the Src SH3 domain: development of a general model for SH3-ligand interactions.; Science, 266:1241-1247, 1994; PubMed: 7526465

実験手法

SOLUTION NMR