1PM7

RmlC (dTDP-6-DEOXY-D-XYLO-4-HEXULOSE 3,5-EPIMERASE)STRUCTURE FROM MYCOBACTERIUM TUBERCULOSIS AND INHIBITOR DESIGN. THE APO STRUCTURE.

Summary for 1PM7

Entry DOI	10.2210/pdb1pm7/pdb
Descriptor	RFBC, ACETATE ION, GLYCEROL, ... (4 entities in total)
Functional Keywords	rmlc, beta barrel, main beta sheet structure, structural genomics, psi, protein structure initiative, tb structural genomics consortium, tbsgc, isomerase
Biological source	Mycobacterium tuberculosis
Total number of polymer chains	2
Total formula weight	44976.17
Authors	Dong, C.,Naismith, J.H.,TB Structural Genomics Consortium (TBSGC) (deposition date: 2003-06-10, release date: 2003-12-09, Last modification date: 2024-02-14)
Primary citation	Babaoglu, K.,Page, M.A.,Jones, V.C.,McNeil, M.R.,Dong, C.,Naismith, J.H.,Lee, R.E. Novel inhibitors of an emerging target in Mycobacterium tuberculosis; substituted thiazolidinones as inhibitors of dTDP-rhamnose synthesis. Bioorg.Med.Chem.Lett., 13:3227-3230, 2003 Cited by PubMed: 12951098 DOI: 10.1016/S0960-894X(03)00673-5 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.2 Å)

Structure validation