1PKM

THE REFINED THREE-DIMENSIONAL STRUCTURE OF CAT MUSCLE (M1) PYRUVATE KINASE, AT A RESOLUTION OF 2.6 ANGSTROMS

Summary for 1PKM

Entry DOI	10.2210/pdb1pkm/pdb
Descriptor	M1 PYRUVATE KINASE (1 entity in total)
Functional Keywords	pyruvate kinase, kinase
Biological source	Felis catus (domestic cat)
Total number of polymer chains	1
Total formula weight	57997.85
Authors	Allen, S.C.,Muirhead, H. (deposition date: 1995-07-13, release date: 1995-10-15, Last modification date: 2024-02-14)
Primary citation	Allen, S.C.,Muirhead, H. Refined three-dimensional structure of cat-muscle (M1) pyruvate kinase at a resolution of 2.6 A. Acta Crystallogr.,Sect.D, 52:499-504, 1996 Cited by PubMed Abstract: The three-dimensional structure of cat-muscle pyoruvate kinase has been refined at a resolution of 2.6 A. The details of the structure permit interpretation of the original heavy-atom studies and give insight into the importance of conserved residues in pyruvate kinases and the allosteric behaviour of the enzyme. There are a small number of essential residues which determine the relative orientations of domains and the precise nature of intersubunit contacts. Arginine residues are particularly important. PubMed: 15299671 DOI: 10.1107/S0907444995016040 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.6 Å)

Structure validation