1PJS

The co-crystal structure of CysG, the multifunctional methyltransferase/dehydrogenase/ferrochelatase for siroheme synthesis, in complex with it NAD cofactor

1PJS の概要

• エントリーDOI: 10.2210/pdb1pjs/pdb
• 関連するPDBエントリー: 1PJQ 1PJT
• 分子名称: Siroheme synthase, S-ADENOSYL-L-HOMOCYSTEINE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ... (6 entities in total)
• 機能のキーワード: rossmann fold, nucleotide binding motif, sah, sam, nad, phosphoserine, transferase-oxidoreductase-lyase complex, transferase/oxidoreductase/lyase
• 由来する生物種: Salmonella typhimurium
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 103063.94

構造登録者

Stroupe, M.E.,Leech, H.K.,Daniels, D.S.,Warren, M.J.,Getzoff, E.D. (登録日: 2003-06-03, 公開日: 2003-12-02, 最終更新日: 2023-08-16)

• 主引用文献: Stroupe, M.E.,Leech, H.K.,Daniels, D.S.,Warren, M.J.,Getzoff, E.D.; CysG structure reveals tetrapyrrole-binding features and novel regulation of siroheme biosynthesis.; Nat.Struct.Biol., 10:1064-1073, 2003; PubMed: 14595395; DOI: 10.1038/nsb1007

実験手法

X-RAY DIFFRACTION (2.4 Å)