1PJP

THE 2.2 A CRYSTAL STRUCTURE OF HUMAN CHYMASE IN COMPLEX WITH SUCCINYL-ALA-ALA-PRO-PHE-CHLOROMETHYLKETONE

1PJP の概要

• エントリーDOI: 10.2210/pdb1pjp/pdb
• 関連するBIRD辞書のPRD_ID: PRD_000381
• 分子名称: Chymase, SUCCINYL-ALA-ALA-PRO-PHE-CHLOROMETHYLKETONE INHIBITOR, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (5 entities in total)
• 機能のキーワード: human chymase, serine proteinase, dipeptidyl carboxypeptidase, angiotensin, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
• 由来する生物種: Homo sapiens (human); 詳細
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 26038.70

構造登録者

Pereira, P.J.B.,Wang, Z.M.,Rubin, H.,Huber, R.,Bode, W.,Schechter, N.M.,Strobl, S. (登録日: 1998-09-07, 公開日: 1999-03-02, 最終更新日: 2024-04-24)

• 主引用文献: Pereira, P.J.,Wang, Z.M.,Rubin, H.,Huber, R.,Bode, W.,Schechter, N.M.,Strobl, S.; The 2.2 A crystal structure of human chymase in complex with succinyl-Ala-Ala-Pro-Phe-chloromethylketone: structural explanation for its dipeptidyl carboxypeptidase specificity.; J.Mol.Biol., 286:163-173, 1999; PubMed: 9931257; DOI: 10.1006/jmbi.1998.2462

実験手法

X-RAY DIFFRACTION (2.2 Å)