1PFG

Strategy to design inhibitors: Structure of a complex of Proteinase K with a designed octapeptide inhibitor N-Ac-Pro-Ala-Pro-Phe-DAla-Ala-Ala-Ala-NH2 at 2.5A resolution

1PFG の概要

• エントリーDOI: 10.2210/pdb1pfg/pdb
• 分子名称: Proteinase K, N-Ac-PAPFAAAA-NH2 (3 entities in total)
• 機能のキーワード: proteinase k, octapeptide, inhibitor, complex, hydrolase, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
• 由来する生物種: Engyodontium album; 詳細
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 29697.69

構造登録者

Saxena, A.K.,Singh, T.P.,Peters, K.,Fittkau, S.,Betzel, C. (登録日: 2003-05-27, 公開日: 2003-06-10, 最終更新日: 2023-10-25)

• 主引用文献: Saxena, A.K.,Singh, T.P.,Peters, K.,Fittkau, S.,Betzel, C.; Strategy to design peptide inhibitors: structure of a complex of proteinase K with a designed octapeptide inhibitor N-Ac-Pro-Ala-Pro-Phe-DAla-Ala-Ala-Ala-NH2 at 2.5 A resolution.; Protein Sci., 5:2453-2458, 1996; PubMed: 8976553; DOI: 10.1002/pro.5560051207

実験手法

X-RAY DIFFRACTION (2.5 Å)