1P5E
The structure of phospho-CDK2/cyclin A in complex with the inhibitor 4,5,6,7-tetrabromobenzotriazole (TBS)
Summary for 1P5E
Entry DOI | 10.2210/pdb1p5e/pdb |
Descriptor | Cell division protein kinase 2, Cyclin A2, 4,5,6,7-TETRABROMOBENZOTRIAZOLE, ... (4 entities in total) |
Functional Keywords | kinase inhibitor, cdk2, tbs, cell cycle |
Biological source | Homo sapiens (human) More |
Cellular location | Cytoplasm, cytoskeleton, microtubule organizing center, centrosome: P24941 Nucleus : P20248 |
Total number of polymer chains | 4 |
Total formula weight | 128405.10 |
Authors | De Moliner, E.,Brown, N.R.,Johnson, L.N. (deposition date: 2003-04-26, release date: 2003-07-01, Last modification date: 2016-12-21) |
Primary citation | De Moliner, E.,Brown, N.R.,Johnson, L.N. Alternative binding modes of an inhibitor to two different kinases Eur.J.Biochem., 270:1-8, 2003 Cited by PubMed: 12869192DOI: 10.1046/j.1432-1033.2003.03697.x PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.22 Å) |
Structure validation
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