1P5E
The structure of phospho-CDK2/cyclin A in complex with the inhibitor 4,5,6,7-tetrabromobenzotriazole (TBS)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C (A, C) | Cell division protein kinase 2 | polymer | 299 | 34143.5 | 2 | UniProt (P24941) Pfam (PF00069) | Homo sapiens (human) | p33 protein kinase |
| 2 | B, D (B, D) | Cyclin A2 | polymer | 258 | 29624.3 | 2 | UniProt (P20248) Pfam (PF00134) Pfam (PF02984) | Homo sapiens (human) | Cyclin A |
| 3 | E, F (A, C) | 4,5,6,7-TETRABROMOBENZOTRIAZOLE | non-polymer | 434.7 | 2 | Chemie (TBS) | |||
| 4 | G, H, I, J (A, B, C, D) | water | water | 18.0 | 242 | Chemie (HOH) |
Sequence modifications
A, C: 1 - 298 (UniProt: P24941)
| PDB | External Database | Details |
|---|---|---|
| Ser 0 | - | CLONING ARTIFACT |
| Tpo 160 | Thr 160 | MODIFIED RESIDUE |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 127535.7 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 869.4 | |
| All* | Total formula weight | 128405.1 |
