1P57

Extracellular domain of human hepsin

Summary for 1P57

• Entry DOI: 10.2210/pdb1p57/pdb
• Descriptor: Serine protease hepsin, 2-{5-[AMINO(IMINIO)METHYL]-1H-BENZIMIDAZOL-2-YL}BENZENOLATE, ... (4 entities in total)
• Functional Keywords: srcr, scavenger receptor cysteine-rich domain, serine protease, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
• Biological source: Homo sapiens (human); More
• Cellular location: Cell membrane ; Single-pass type II membrane protein : P05981 P05981
• Total number of polymer chains: 2
• Total formula weight: 40347.68

Authors

Somoza, J.R.,Ho, J.D.,Luong, C.,Sprengeler, P.A.,Mortara, K.,Shrader, W.D.,Sperandio, D.,Chan, H.,McGrath, M.E.,Katz, B.A. (deposition date: 2003-04-25, release date: 2004-01-20, Last modification date: 2023-08-16)

• Primary citation: Somoza, J.R.,Ho, J.D.,Luong, C.,Ghate, M.,Sprengeler, P.A.,Mortara, K.,Shrader, W.D.,Sperandio, D.,Chan, H.,McGrath, M.E.,Katz, B.A.; The Structure of the Extracellular Region of Human Hepsin Reveals a Serine Protease Domain and a Novel Scavenger Receptor Cysteine-Rich (SRCR) Domain; Structure, 11:1123-1131, 2003; PubMed: 12962630; DOI: 10.1016/S0969-2126(03)00148-5

Experimental method

X-RAY DIFFRACTION (1.75 Å)