1P49

Structure of Human Placental Estrone/DHEA Sulfatase

1P49 の概要

• エントリーDOI: 10.2210/pdb1p49/pdb
• 分子名称: STERYL-SULFATASE, octyl beta-D-glucopyranoside, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (6 entities in total)
• 機能のキーワード: steroid biosynthesis, steroid sulfatase, estrone sulfate, dehydroepiandrosterone sulfate, human placental enzyme, endoplasmic reticulum membrane-bound, hydrolase
• 由来する生物種: Homo sapiens (human)
• 細胞内の位置: Endoplasmic reticulum membrane; Multi-pass membrane protein: P08842
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 64214.03

構造登録者

Hernandez-Guzman, F.G.,Higashiyama, T.,Pangborn, W.,Osawa, Y.,Ghosh, D. (登録日: 2003-04-21, 公開日: 2003-08-12, 最終更新日: 2020-07-29)

• 主引用文献: Hernandez-Guzman, F.G.,Higashiyama, T.,Pangborn, W.,Osawa, Y.,Ghosh, D.; Structure of Human Estrone Sulfatase Suggests Functional Roles of Membrane Association; J.Biol.Chem., 278:22989-22997, 2003; PubMed: 12657638; DOI: 10.1074/jbc.M211497200

実験手法

X-RAY DIFFRACTION (2.6 Å)