1P45
Targeting tuberculosis and malaria through inhibition of enoyl reductase: compound activity and structural data
1P45 の概要
エントリーDOI | 10.2210/pdb1p45/pdb |
関連するPDBエントリー | 1P44 |
分子名称 | Enoyl-[acyl-carrier-protein] reductase [NADH], NICOTINAMIDE-ADENINE-DINUCLEOTIDE, TRICLOSAN, ... (4 entities in total) |
機能のキーワード | inha, short chain dehydrogenase reductase, triclosan, rossmann fold, enoyl-acp reductase, structural genomics, psi, protein structure initiative, tb structural genomics consortium, tbsgc, oxidoreductase |
由来する生物種 | Mycobacterium tuberculosis |
タンパク質・核酸の鎖数 | 2 |
化学式量合計 | 59305.04 |
構造登録者 | Kuo, M.R.,Morbidoni, H.R.,Alland, D.,Sneddon, S.F.,Gourlie, B.B.,Staveski, M.M.,Leonard, M.,Gregory, J.S.,Janjigian, A.D.,Yee, C.,Musser, J.M.,Kreiswirth, B.N.,Iwamoto, H.,Perozzo, R.,Jacobs Jr., W.R.,Sacchettini, J.C.,Fidock, D.A.,TB Structural Genomics Consortium (TBSGC) (登録日: 2003-04-21, 公開日: 2003-09-16, 最終更新日: 2019-07-24) |
主引用文献 | Kuo, M.R.,Morbidoni, H.R.,Alland, D.,Sneddon, S.F.,Gourlie, B.B.,Staveski, M.M.,Leonard, M.,Gregory, J.S.,Janjigian, A.D.,Yee, C.,Musser, J.M.,Kreiswirth, B.,Iwamoto, H.,Perozzo, R.,Jacobs, W.R.,Sacchettini, J.C.,Fidock, D.A. Targeting tuberculosis and malaria through inhibition of Enoyl reductase: compound activity and structural data. J.Biol.Chem., 278:20851-20859, 2003 Cited by PubMed: 12606558DOI: 10.1074/jbc.M211968200 主引用文献が同じPDBエントリー |
実験手法 | X-RAY DIFFRACTION (2.6 Å) |
構造検証レポート
検証レポート(詳細版)をダウンロード