1P2K

Structural consequences of accommodation of four non-cognate amino-acid residues in the S1 pocket of bovine trypsin and chymotrypsin

1P2K の概要

• エントリーDOI: 10.2210/pdb1p2k/pdb
• 関連するPDBエントリー: 1P2I 1P2J 1P2M 1P2N 1P2O 1P2Q
• 分子名称: Trypsinogen, cationic, Pancreatic trypsin inhibitor, CALCIUM ION, ... (5 entities in total)
• 機能のキーワード: trypsin; chymotrypsin; serine proteinase; bovine pancreatic trypsin inhibitor; protein-protein interaction; non-cognate binding; s1 pocket; primary specificity; crystal structure, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
• 由来する生物種: Bos taurus (cattle); 詳細
• 細胞内の位置: Secreted, extracellular space: P00760; Secreted: P00974
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 30035.97

構造登録者

Helland, R.,Czapinska, H.,Leiros, I.,Olufsen, M.,Otlewski, J.,Smalaas, A.O. (登録日: 2003-04-15, 公開日: 2004-04-20, 最終更新日: 2023-08-16)

• 主引用文献: Helland, R.,Czapinska, H.,Leiros, I.,Olufsen, M.,Otlewski, J.,Smalaas, A.O.; Structural consequences of accommodation of four non-cognate amino acid residues in the S1 pocket of bovine trypsin and chymotrypsin.; J.Mol.Biol., 333:845-861, 2003; PubMed: 14568540; DOI: 10.1016/j.jmb.2003.08.059

実験手法

X-RAY DIFFRACTION (1.6 Å)