1OXR

Aspirin induces its Anti-inflammatory effects through its specific binding to Phospholipase A2: Crystal structure of the complex formed between Phospholipase A2 and Aspirin at 1.9A resolution

Summary for 1OXR

Entry DOI	10.2210/pdb1oxr/pdb
Related	1LFF 1LN8
Descriptor	Phospholipase A2 isoform 3, 2-(ACETYLOXY)BENZOIC ACID, CALCIUM ION, ... (4 entities in total)
Functional Keywords	o-acetyl-oxy phenol, complex, pla2, naja naja sagittifera, hydrolase
Biological source	Naja sagittifera
Cellular location	Secreted: P60045
Total number of polymer chains	1
Total formula weight	13403.83
Authors	Singh, R.K.,Ethayathulla, A.S.,Jabeen, T.,Sharma, S.,Kaur, P.,Srinivasan, A.,Singh, T.P. (deposition date: 2003-04-03, release date: 2004-04-27, Last modification date: 2023-08-16)
Primary citation	Singh, R.K.,Ethayathulla, A.S.,Jabeen, T.,Sharma, S.,Kaur, P.,Singh, T.P. Aspirin induces its anti-inflammatory effects through its specific binding to phospholipase A2: crystal structure of the complex formed between phospholipase A2 and aspirin at 1.9 angstroms resolution. J.Drug Target., 13:113-119, 2005 Cited by PubMed: 15823962 DOI: 10.1080/10611860400024078 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.93 Å)

Structure validation