1OW3

Crystal Structure of RhoA.GDP.MgF3-in Complex with RhoGAP

Summary for 1OW3

Entry DOI	10.2210/pdb1ow3/pdb
Descriptor	Rho-GTPase-activating protein 1, Transforming protein RhoA, MAGNESIUM ION, ... (6 entities in total)
Functional Keywords	complex, gtpase, gap, transition state, gene regulation-signaling protein complex, gene regulation/signaling protein
Biological source	Homo sapiens (human) More
Cellular location	Cytoplasm: Q07960 Cell membrane; Lipid-anchor; Cytoplasmic side: P61586
Total number of polymer chains	2
Total formula weight	49759.36
Authors	Graham, D.L.,Lowe, P.N.,Grime, G.W.,Marsh, M.,Rittinger, K.,Smerdon, S.J.,Gamblin, S.J.,Eccleston, J.F. (deposition date: 2003-03-28, release date: 2003-05-06, Last modification date: 2023-08-16)
Primary citation	Graham, D.L.,Lowe, P.N.,Grime, G.W.,Marsh, M.,Rittinger, K.,Smerdon, S.J.,Gamblin, S.J.,Eccleston, J.F. MgF(3)(-) as a Transition State Analog of Phosphoryl Transfer Chem.Biol., 9:375-381, 2002 Cited by PubMed: 11927263 DOI: 10.1016/S1074-5521(02)00112-6 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.8 Å)

Structure validation