1OW3
Crystal Structure of RhoA.GDP.MgF3-in Complex with RhoGAP
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Rho-GTPase-activating protein 1 | polymer | 242 | 27444.5 | 1 | UniProt (Q07960) Pfam (PF00620) In PDB | Homo sapiens (human) | GTPase-activating protein rhoOGAP, Rho-related small GTPase protein activator, CDC42 GTPase-activating protein, p50-rhoGAP |
| 2 | B | Transforming protein RhoA | polymer | 193 | 21766.1 | 1 | UniProt (P61586) Pfam (PF00071) In PDB | Homo sapiens (human) | H12 |
| 3 | B | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
| 4 | B | GUANOSINE-5'-DIPHOSPHATE | non-polymer | 443.2 | 1 | Chemie (GDP) | |||
| 5 | B | TRIFLUOROMAGNESATE | non-polymer | 81.3 | 1 | Chemie (MGF) | |||
| 6 | water | water | 18.0 | 374 | Chemie (HOH) |
Sequence modifications
B: 1 - 193 (UniProt: P61586)
| PDB | External Database | Details |
|---|---|---|
| Asn 25 | Phe 25 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 49210.6 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 548.8 | |
| All* | Total formula weight | 49759.4 |
