1OV4

Crystal structure of human DHEA-ST complexed with androsterone

Summary for 1OV4

Related1J99 1EFH
DescriptorAlcohol sulfotransferase, SULFATE ION, (3Beta,5alpha)-3-Hydroxyandrostan-17-one, ... (4 entities in total)
Functional Keywordsalpha/beta fold, transferase
Biological sourceHomo sapiens (human)
Cellular locationCytoplasm Q06520
Total number of polymer chains1
Total molecular weight35103.21
Authors
Chang, H.J.,Shi, R.,Rhese, P.,Lin, S.X. (deposition date: 2003-03-25, release date: 2004-02-17, Last modification date: 2013-07-03)
Primary citation
Chang, H.J.,Shi, R.,Rehse, P.,Lin, S.X.
Identifying androsterone (ADT) as a cognate substrate for human dehydroepiandrosterone sulfotransferase (DHEA-ST) important for steroid homeostasis: structure of the enzyme-ADT complex.
J.Biol.Chem., 279:2689-2696, 2004
PubMed: 14573603 (PDB entries with the same primary citation)
DOI: 10.1074/jbc.M310446200
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.7 Å)
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Structure validation

ClashscoreRamachandran outliersSidechain outliers170 2.3%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
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171916
PDB entries from 2020-12-02