1OTX

Purine Nucleoside Phosphorylase M64V mutant

Summary for 1OTX

Entry DOI	10.2210/pdb1otx/pdb
Related	1A90 1ECP 1OTY
Descriptor	Purine nucleoside phosphorylase, PHOSPHATE ION (3 entities in total)
Functional Keywords	empty, pnp, transferase
Biological source	Escherichia coli
Total number of polymer chains	3
Total formula weight	77740.96
Authors	Ealick, S.E.,Bennett, E.M.,Anand, R.,Secrist, J.A.,Parker, W.B.,Hassan, A.E.,Allan, P.W.,McPherson, D.T.,Sorscher, E.J. (deposition date: 2003-03-23, release date: 2004-02-17, Last modification date: 2023-08-16)
Primary citation	Bennett, E.M.,Anand, R.,Allan, P.W.,Hassan, A.E.,Hong, J.S.,Levasseur, D.N.,McPherson, D.T.,Parker, W.B.,Secrist, J.A.,Sorscher, E.J.,Townes, T.M.,Waud, W.R.,Ealick, S.E. Designer gene therapy using an Escherichia coli purine nucleoside phosphorylase/prodrug system. Chem.Biol., 10:1173-1181, 2003 Cited by PubMed: 14700625 DOI: 10.1016/j.chembiol.2003.11.008 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.7 Å)

Structure validation