1ONO

IspC Mn2+ complex

Summary for 1ONO

Entry DOI	10.2210/pdb1ono/pdb
Related	1ONN 1ONP
Descriptor	1-deoxy-D-xylulose 5-phosphate reductoisomerase, MANGANESE (II) ION (3 entities in total)
Functional Keywords	isoprenoid biosynthesis, mevalonate-independent pathway, ispc, oxidoreductase
Biological source	Escherichia coli
Total number of polymer chains	2
Total formula weight	86973.63
Authors	Steinbacher, S.,Kaiser, J.,Eisenreich, W.,Huber, R.,Bacher, A.,Rohdich, F. (deposition date: 2003-02-28, release date: 2003-03-18, Last modification date: 2023-10-25)
Primary citation	Steinbacher, S.,Kaiser, J.,Eisenreich, W.,Huber, R.,Bacher, A.,Rohdich, F. Structural basis of fosmidomycin action revealed by the complex with 2-C-methyl-D-erythritol 4-phosphate synthase (IspC). Implications for the catalytic mechanism and anti-malaria drug development. J.BIOL.CHEM., 278:18401-18407, 2003 Cited by PubMed: 12621040 DOI: 10.1074/jbc.M300993200 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.5 Å)

Structure validation