1ONG

SHV-1 beta-lactamase with a penem inhibitor

Summary for 1ONG

Entry DOI	10.2210/pdb1ong/pdb
Related	1G56 1ONH 1SHV
Descriptor	BETA-LACTAMASE SHV-1, CYCLOHEXYL-HEXYL-BETA-D-MALTOSIDE, 7-(5,6-DIHYDRO-8H-IMIDAZO[2,1-C][1,4]OXAZIN-2-YL)-6-FORMYL-2,7-DIHYDRO- [1,4]THIAZEPINE-3-CARBOXYLIC ACID, ... (4 entities in total)
Functional Keywords	beta-lactam hydrolase, penicillinase, detergent binding, drug design, hydrolase
Biological source	Klebsiella pneumoniae
Total number of polymer chains	1
Total formula weight	30231.54
Authors	Nukaga, M.,Mayama, K.,Bonomo, R.A.,Knox, J.R. (deposition date: 2003-02-27, release date: 2003-12-09, Last modification date: 2023-08-16)
Primary citation	Nukaga, M.,Abe, T.,Venkatesan, A.M.,Mansour, T.S.,Bonomo, R.A.,Knox, J.R. Inhibition of Class A and Class C Beta-Lactamases by Penems: Crystallographic Structures of a Novel 1,4-Thiazepine Intermediate Biochemistry, 42:13152-13159, 2003 Cited by PubMed: 14609325 DOI: 10.1021/bi034986b PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.1 Å)

Structure validation