1OKE

Crystal structure of the dengue 2 virus envelope protein in complex with n-octyl-beta-D-glucoside

1OAM」から置き換えられました

1OKE の概要

関連するPDBエントリー1L9K 1OAM 1OAN 1OK8
分子名称MAJOR ENVELOPE PROTEIN E, N-ACETYL-D-GLUCOSAMINE, BETA-L-FUCOSE, ... (6 entities in total)
機能のキーワードviral protein, membrane fusion, flavivirus, fusion peptide, low-ph conformational change, class 2 fusion protein
由来する生物種DENGUE VIRUS TYPE 2
細胞内の位置Capsid protein C: Virion (Potential). Peptide pr: Secreted (By similarity). Small envelope protein M: Virion membrane; Multi-pass membrane protein (By similarity). Envelope protein E: Virion membrane; Multi- pass membrane protein (By similarity). Non-structural protein 1: Secreted. Non-structural protein 2A-alpha: Host endoplasmic reticulum membrane; Multi-pass membrane protein (Potential). Non-structural protein 2A: Host endoplasmic reticulum membrane; Multi-pass membrane protein (Potential). Serine protease subunit NS2B: Host endoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side (By similarity). Serine protease NS3: Host endoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side (By similarity). Non-structural protein 4A: Host endoplasmic reticulum membrane; Multi-pass membrane protein (By similarity). Non-structural protein 4B: Host endoplasmic reticulum membrane; Multi-pass membrane protein (By similarity). RNA-directed RNA polymerase NS5: Host endoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side (By similarity) P12823
ポリマー鎖数2
分子量合計90239.39
構造登録者
Modis, Y.,Harrison, S.C. (登録日: 2003-07-22, 公開日: 2003-07-24, 最終更新日: 2012-01-18)
主引用文献
Modis, Y.,Ogata, S.,Clements, D.,Harrison, S.C.
A Ligand-Binding Pocket in the Dengue Virus Envelope Glycoprotein.
Proc.Natl.Acad.Sci.USA, 100:6986-, 2003
PubMed: 12759475 (主引用文献が同じPDBエントリー)
DOI: 10.1073/PNAS.0832193100
MImport into Mendeley
実験手法
X-RAY DIFFRACTION (2.4 Å)
NMR情報
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構造検証レポート

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.301231.7%6.0%5.8%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
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