1O9S

Crystal structure of a ternary complex of the human histone methyltransferase SET7/9

1O9S の概要

• エントリーDOI: 10.2210/pdb1o9s/pdb
• 関連するPDBエントリー: 1H3I
• 分子名称: HISTONE-LYSINE N-METHYLTRANSFERASE, H3 LYSINE-4 SPECIFIC, GENE FRAGMENT FOR HISTONE H3, S-ADENOSYL-L-HOMOCYSTEINE, ... (4 entities in total)
• 機能のキーワード: methylation, histone h3, methyltransferase, transferase
• 由来する生物種: HOMO SAPIENS (HUMAN); 詳細
• 細胞内の位置: Nucleus: Q8WTS6
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 61071.98

構造登録者

Xiao, B.,Jing, C.,Wilson, J.R.,Walker, P.A.,Vasisht, N.,Kelly, G.,Howell, S.,Taylor, I.A.,Blackburn, G.M.,Gamblin, S.J. (登録日: 2002-12-18, 公開日: 2003-02-06, 最終更新日: 2023-12-13)

• 主引用文献: Xiao, B.,Jing, C.,Wilson, J.R.,Walker, P.A.,Vasisht, N.,Kelly, G.,Howell, S.,Taylor, I.A.,Blackburn, G.M.,Gamblin, S.J.; Structure and Catalytic Mechanism of the Human Histone Methyltransferase Set7/9; Nature, 421:652-, 2003; PubMed: 12540855; DOI: 10.1038/NATURE01378

実験手法

X-RAY DIFFRACTION (1.75 Å)