1O7D

The structure of the bovine lysosomal a-mannosidase suggests a novel mechanism for low pH activation

1O7D の概要

• エントリーDOI: 10.2210/pdb1o7d/pdb
• 分子名称: Lysosomal alpha-mannosidase, ZINC ION, SULFATE ION, ... (12 entities in total)
• 機能のキーワード: hydrolase, glycosyl hydrolase family 38, a-mannosidase, lysosomal
• 由来する生物種: Bos taurus (Bovine); 詳細
• タンパク質・核酸の鎖数: 5
• 化学式量合計: 111487.00

構造登録者

Heikinheimo, P.,Helland, R.,Leiros, H.S.,Leiros, I.,Karlsen, S.,Evjen, G.,Ravelli, R.,Schoehn, G.,Ruigrok, R.,Tollersrud, O.-K.,Mcsweeney, S.,Hough, E. (登録日: 2002-10-30, 公開日: 2003-03-20, 最終更新日: 2023-12-13)

• 主引用文献: Heikinheimo, P.,Helland, R.,Leiros, H.S.,Leiros, I.,Karlsen, S.,Evjen, G.,Ravelli, R.,Schoehn, G.,Ruigrok, R.,Tollersrud, O.-K.,Mcsweeney, S.,Hough, E.; The Structure of Bovine Lysosomal Alpha-Mannosidase Suggests a Novel Mechanism for Low-Ph Activation; J.Mol.Biol., 327:631-, 2003; PubMed: 12634058; DOI: 10.1016/S0022-2836(03)00172-4

実験手法

X-RAY DIFFRACTION (2.7 Å)