1O5R
Crystal structure of adenosine deaminase complexed with a potent inhibitor
Summary for 1O5R
Entry DOI | 10.2210/pdb1o5r/pdb |
Related | 1UML |
Descriptor | Adenosine deaminase, ZINC ION, 1-[(1R)-3-(6-{[(BENZYLAMINO)CARBONYL]AMINO}-1H-INDOL-1-YL)-1-(HYDROXYMETHYL)PROPYL]-1H-IMIDAZOLE-4-CARBOXAMIDE, ... (4 entities in total) |
Functional Keywords | beta barrel, zinc, hydrolase |
Biological source | Bos taurus (cattle) |
Cellular location | Cell membrane ; Peripheral membrane protein ; Extracellular side : P56658 |
Total number of polymer chains | 1 |
Total formula weight | 40853.58 |
Authors | Kinoshita, T. (deposition date: 2003-10-05, release date: 2004-09-21, Last modification date: 2023-12-27) |
Primary citation | Terasaka, T.,Kinoshita, T.,Kuno, M.,Seki, N.,Tanaka, K.,Nakanishi, I. Structure-based design, synthesis, and structure-activity relationship studies of novel non-nucleoside adenosine deaminase inhibitors J.Med.Chem., 47:3730-3743, 2004 Cited by PubMed: 15239652DOI: 10.1021/jm0306374 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.35 Å) |
Structure validation
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