1O4X

TERNARY COMPLEX OF THE DNA BINDING DOMAINS OF THE OCT1 AND SOX2 TRANSCRIPTION FACTORS WITH A 19MER OLIGONUCLEOTIDE FROM THE HOXB1 REGULATORY ELEMENT

1O4X の概要

• エントリーDOI: 10.2210/pdb1o4x/pdb
• 分子名称: 5'-D(*TP*GP*TP*CP*TP*TP*TP*GP*TP*CP*AP*TP*GP*CP*TP*AP*AP*TP*G)-3', 5'-D(*CP*AP*TP*TP*AP*GP*CP*AP*TP*GP*AP*CP*AP*AP*AP*GP*AP*CP*A)-3', transcription factor Oct-1, ... (4 entities in total)
• 機能のキーワード: oct1, pou, pous, pouhd, sox2, hmg-box, transcription factors, dna, protein-dna complex, transcription-dna complex, transcription/dna
• 由来する生物種: Homo sapiens (human); 詳細
• 細胞内の位置: Nucleus: P14859 P48431
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 41446.89

構造登録者

Clore, G.M.,Williams, D.C. (登録日: 2003-07-17, 公開日: 2004-01-27, 最終更新日: 2023-12-27)

• 主引用文献: Williams, D.C.,Cai, M.,Clore, G.M.; Molecular basis for synergistic transcriptional activation by Oct1 and Sox2 revealed from the solution structure of the 42-kDa Oct1.Sox2.Hoxb1-DNA ternary transcription factor complex.; J.Biol.Chem., 279:1449-1457, 2004; PubMed: 14559893; DOI: 10.1074/jbc.M309790200

実験手法

SOLUTION NMR