1O28

Crystal structure of Thymidylate Synthase Complementing Protein (TM0449) from Thermotoga maritima with FdUMP at 2.1 A resolution

Summary for 1O28

Entry DOI	10.2210/pdb1o28/pdb
Related	1O24 1O25 1O26 1O27 1O29 1O2A 1O2B
Descriptor	Thymidylate synthase thyX, 5-FLUORO-2'-DEOXYURIDINE-5'-MONOPHOSPHATE, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ... (5 entities in total)
Functional Keywords	tm0449, thymidylate synthase complementing protein, structural genomics, jcsg, joint center for structural genomics, psi, protein structure initiative, transferase
Biological source	Thermotoga maritima
Total number of polymer chains	4
Total formula weight	112873.32
Authors	Mathews, I.I.,Deacon, A.M.,Canaves, J.M.,McMullan, D.,Lesley, S.A.,Agarwalla, S.,Kuhn, P.,Joint Center for Structural Genomics (JCSG) (deposition date: 2003-02-18, release date: 2003-06-24, Last modification date: 2023-09-20)
Primary citation	Mathews, I.I.,Deacon, A.M.,Canaves, J.M.,McMullan, D.,Lesley, S.A.,Agarwalla, S.,Kuhn, P. Functional Analysis of Substrate and Cofactor Complex Structures of a Thymidylate Synthase-Complementing Protein Structure, 11:677-690, 2003 Cited by PubMed: 12791256 DOI: 10.1016/S0969-2126(03)00097-2 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.1 Å)

Structure validation