1O23
CRYSTAL STRUCTURE OF LACTOSE SYNTHASE IN THE PRESENCE OF UDP-GLUCOSE
Replaces: 1NT7Replaces: 1JNCSummary for 1O23
Entry DOI | 10.2210/pdb1o23/pdb |
Descriptor | ALPHA-LACTALBUMIN, BETA-1,4-GALACTOSYLTRANSFERASE, CALCIUM ION, ... (9 entities in total) |
Functional Keywords | alpha-lactalbumin; beta, 1, 4-galactosyltransferase; udp-glucose, transferase activator-transferase complex, transferase activator/transferase |
Biological source | Mus musculus (house mouse) More |
Cellular location | Secreted: P29752 Isoform Long: Golgi apparatus, Golgi stack membrane; Single-pass type II membrane protein. Isoform Short: Golgi apparatus, Golgi stack membrane; Single-pass type II membrane protein. Processed beta-1,4-galactosyltransferase 1: Secreted: P08037 |
Total number of polymer chains | 4 |
Total formula weight | 96449.55 |
Authors | Ramakrishnan, B.,Shah, P.S.,Qasba, P.K. (deposition date: 2003-01-29, release date: 2003-02-25, Last modification date: 2023-12-27) |
Primary citation | Ramakrishnan, B.,Shah, P.S.,Qasba, P.K. Alpha-Lactalbumin (La) Stimulates Milk Beta-1,4-Galactosyltransferase I (Beta 4Gal-T1) to Transfer Glucose from Udp-Glucose to N-Acetylglucosamine. Crystal Structure of Beta 4Gal-T1 X La Complex with Udp-Glc. J.Biol.Chem., 276:37665-37671, 2001 Cited by PubMed: 11485999DOI: 10.1074/jbc.M102458200 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.32 Å) |
Structure validation
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