1O07
Crystal Structure of the complex between Q120L/Y150E mutant of AmpC and a beta-lactam inhibitor (MXG)
Summary for 1O07
Entry DOI | 10.2210/pdb1o07/pdb |
Descriptor | Beta-lactamase, POTASSIUM ION, 2-(1-{2-[4-(2-ACETYLAMINO-PROPIONYLAMINO)-4-CARBOXY-BUTYRYLAMINO]-6-AMINO-HEXANOYLAMINO}-2-OXO-ETHYL)-5-METHYLENE-5,6-DIHYDRO-2H-[1,3]THIAZINE-4-CARBOXYLIC ACID, ... (4 entities in total) |
Functional Keywords | enzyme inhibitor complex, beta-lactamase beta-lactam complex, hydrolase |
Biological source | Escherichia coli |
Cellular location | Periplasm: P00811 |
Total number of polymer chains | 2 |
Total formula weight | 80325.26 |
Authors | Meroueh, S.O.,Minasov, G.,Lee, W.,Shoichet, B.K.,Mobashery, S. (deposition date: 2003-02-20, release date: 2003-08-26, Last modification date: 2024-04-03) |
Primary citation | Meroueh, S.O.,Minasov, G.,Lee, W.,Shoichet, B.K.,Mobashery, S. Structural Aspects for Evolution of beta-Lactamases from Penicillin-Binding Proteins J.Am.Chem.Soc., 125:9612-9618, 2003 Cited by PubMed: 12904027DOI: 10.1021/ja034861u PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.71 Å) |
Structure validation
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