1NX0

Structure of Calpain Domain 6 in Complex with Calpastatin DIC

1NX0 の概要

• エントリーDOI: 10.2210/pdb1nx0/pdb
• 関連するPDBエントリー: 1NX1 1NX2 1NX3
• 分子名称: Calcium-dependent protease, small subunit, Calpastatin, Small molecule inhibitor, ... (5 entities in total)
• 機能のキーワード: calcium binding, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
• 由来する生物種: Sus scrofa (pig); 詳細
• 細胞内の位置: Cytoplasm (By similarity): P04574
• タンパク質・核酸の鎖数: 5
• 化学式量合計: 42963.53

構造登録者

Todd, B.,Moore, D.,Deivanayagam, C.C.S.,Lin, G.-D.,Chattopadhyay, D.,Maki, M.,Wang, K.K.W.,Narayana, S.V.L. (登録日: 2003-02-07, 公開日: 2003-08-19, 最終更新日: 2024-02-14)

• 主引用文献: Todd, B.,Moore, D.,Deivanayagam, C.C.S.,Lin, G.-D.,Chattopadhyay, D.,Maki, M.,Wang, K.K.W.,Narayana, S.V.L.; A structural model for the inhibition of calpain by calpastatin: crystal structures of the native domain VI of calpain and its complexes with calpastatin peptide and a small molecule inhibitor.; J.Mol.Biol., 328:131-146, 2003; PubMed: 12684003; DOI: 10.1016/S0022-2836(03)00274-2

実験手法

X-RAY DIFFRACTION (2.3 Å)