1NUN
Crystal Structure Analysis of the FGF10-FGFR2b Complex
Summary for 1NUN
Entry DOI | 10.2210/pdb1nun/pdb |
Descriptor | Fibroblast growth factor-10, fibroblast growth factor receptor 2 isoform 2, SULFATE ION, ... (5 entities in total) |
Functional Keywords | beta-trefoil fold, immunoglobulin-like domain, hormone-growth factor-membrane protein complex, hormone/growth factor/membrane protein |
Biological source | Homo sapiens (human) More |
Cellular location | Secreted (Potential): O15520 Cell membrane; Single-pass type I membrane protein. Isoform 14: Secreted. Isoform 19: Secreted: P21802 |
Total number of polymer chains | 2 |
Total formula weight | 44492.87 |
Authors | Yeh, B.K.,Igarashi, M.,Eliseenkova, A.V.,Plotnikov, A.N.,Sher, I.,Ron, D.,Aaronson, S.A.,Mohammadi, M. (deposition date: 2003-01-31, release date: 2003-02-11, Last modification date: 2011-07-13) |
Primary citation | Yeh, B.K.,Igarashi, M.,Eliseenkova, A.V.,Plotnikov, A.N.,Sher, I.,Ron, D.,Aaronson, S.A.,Mohammadi, M. Structural basis by which alternative splicing confers specificity in fibroblast growth factor receptors. Proc.Natl.Acad.Sci.USA, 100:2266-2271, 2003 Cited by PubMed: 12591959DOI: 10.1073/pnas.0436500100 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.9 Å) |
Structure validation
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