1NT3

HUMAN NEUROTROPHIN-3

Summary for 1NT3

Entry DOI	10.2210/pdb1nt3/pdb
Descriptor	PROTEIN (NEUROTROPHIN-3) (2 entities in total)
Functional Keywords	neurotrophin, growth factor, cystine knot, hormone-growth factor-neuropeptide complex, hormone/growth factor/neuropeptide
Biological source	Homo sapiens (human)
Cellular location	Secreted: P20783
Total number of polymer chains	1
Total formula weight	13649.40
Authors	Butte, M.J.,Hwang, P.K.,Mobley, W.C.,Fletterick, R.J. (deposition date: 1999-05-17, release date: 1999-06-06, Last modification date: 2023-08-16)
Primary citation	Butte, M.J.,Hwang, P.K.,Mobley, W.C.,Fletterick, R.J. Crystal structure of neurotrophin-3 homodimer shows distinct regions are used to bind its receptors. Biochemistry, 37:16846-16852, 1998 Cited by PubMed: 9836577 DOI: 10.1021/bi981254o PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.4 Å)

Structure validation