1NSW

The Crystal Structure of the K18G Mutant of the thioredoxin from Alicyclobacillus acidocaldarius

1NSW の概要

• エントリーDOI: 10.2210/pdb1nsw/pdb
• 関連するPDBエントリー: 1NWL 1QUW 2TRX
• 分子名称: THIOREDOXIN (2 entities in total)
• 機能のキーワード: thermostability, thioredoxin, electron transport
• 由来する生物種: Alicyclobacillus acidocaldarius
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 46052.65

構造登録者

Bartolucci, S.,De Simone, G.,Galdiero, S.,Improta, R.,Menchise, V.,Pedone, C.,Pedone, E.,Saviano, M. (登録日: 2003-01-28, 公開日: 2003-08-05, 最終更新日: 2024-10-30)

主引用文献

Bartolucci, S.,De Simone, G.,Galdiero, S.,Improta, R.,Menchise, V.,Pedone, C.,Pedone, E.,Saviano, M.
An integrated structural and computational study of the thermostability of two thioredoxin mutants from Alicyclobacillus acidocaldarius
J.Bacteriol., 185:4285-4289, 2003

PubMed Abstract: We report a crystallographic and computational analysis of two mutant forms of the Alicyclobacillus acidocaldarius thioredoxin (BacTrx) done in order to evaluate the contribution of two specific amino acids to the thermostability of BacTrx. Our results suggest that the thermostability of BacTrx may be modulated by mutations affecting the overall electrostatic energy of the protein.

PubMed: 12837806
DOI: 10.1128/JB.185.14.4285-4289.2003

実験手法

X-RAY DIFFRACTION (1.9 Å)