1NR6
MICROSOMAL CYTOCHROME P450 2C5/3LVDH COMPLEX WITH DICLOFENAC
Summary for 1NR6
| Entry DOI | 10.2210/pdb1nr6/pdb |
| Related | 1DT6 1N6B |
| Descriptor | CYTOCHROME P450 2C5, SULFATE ION, PROTOPORPHYRIN IX CONTAINING FE, ... (5 entities in total) |
| Functional Keywords | membrane protein, progesterone 21-hydroxylase, benzo(a), pyrene hydroxylase, estradiol 2-hydroxylase, p450, cyp2c5, diclofenac complex, oxidoreductase |
| Biological source | Oryctolagus cuniculus (rabbit) |
| Cellular location | Endoplasmic reticulum membrane (By similarity): P00179 |
| Total number of polymer chains | 1 |
| Total formula weight | 54989.01 |
| Authors | Wester, M.R.,Johnson, E.F.,Stout, C.D. (deposition date: 2003-01-23, release date: 2003-08-12, Last modification date: 2023-08-16) |
| Primary citation | WESTER, M.R.,JOHNSON, E.F.,Marques-Soares, C.,Dijols, S.,Dansette, P.M.,Mansuy, D.,STOUT, C.D. Structure of Mammalian Cytochrome P450 2C5 Complexed with Diclofenac at 2.1 A Resolution: Evidence for an Induced Fit Model of Substrate Binding Biochemistry, 42:9335-9345, 2003 Cited by PubMed: 12899620DOI: 10.1021/bi034556l PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.1 Å) |
Structure validation
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