1NR6
MICROSOMAL CYTOCHROME P450 2C5/3LVDH COMPLEX WITH DICLOFENAC
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | CYTOCHROME P450 2C5 | polymer | 473 | 53884.3 | 1 | UniProt (P00179) Pfam (PF00067) | Oryctolagus cuniculus (rabbit) | CYPIIC5, PROGESTERONE 21-HYDROXYLASE, P450 1, P450IIC5 |
| 2 | B, C (A) | SULFATE ION | non-polymer | 96.1 | 2 | Chemie (SO4) | |||
| 3 | D (A) | PROTOPORPHYRIN IX CONTAINING FE | non-polymer | 616.5 | 1 | Chemie (HEM) | |||
| 4 | E (A) | 2-[2,6-DICHLOROPHENYL)AMINO]BENZENEACETIC ACID | non-polymer | 296.1 | 1 | Chemie (DIF) | |||
| 5 | F (A) | water | water | 18.0 | 262 | Chemie (HOH) |
Sequence modifications
A: 19 - 487 (UniProt: P00179)
| PDB | External Database | Details |
|---|---|---|
| Met 19 | - | engineered mutation |
| Ala 20 | - | engineered mutation |
| Lys 21 | - | engineered mutation |
| Lys 22 | - | engineered mutation |
| Thr 23 | - | engineered mutation |
| Ser 24 | - | engineered mutation |
| Ser 25 | - | engineered mutation |
| Lys 26 | - | engineered mutation |
| His 202 | Asn 202 | engineered mutation |
| Glu 206 | Arg 206 | engineered mutation |
| Leu 207 | Ile 207 | engineered mutation |
| Gly 209 | Ser 209 | engineered mutation |
| Thr 210 | Ser 210 | engineered mutation |
| His 488 | - | expression tag |
| His 489 | - | expression tag |
| His 490 | - | expression tag |
| His 491 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 53884.3 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 1104.8 | |
| All* | Total formula weight | 54989.0 |
