1NQ7
Characterization of ligands for the orphan nuclear receptor RORbeta
Summary for 1NQ7
Entry DOI | 10.2210/pdb1nq7/pdb |
Descriptor | NUCLEAR RECEPTOR ROR-BETA, STEROID RECEPTOR COACTIVATOR-1, 7-(3,5-DITERT-BUTYLPHENYL)-3-METHYLOCTA-2,4,6-TRIENOIC ACID, ... (4 entities in total) |
Functional Keywords | ligand-binding domain, retinoids, retinoic acid, synthetic ligand, antagonist, transcription |
Biological source | Rattus norvegicus (Norway rat) More |
Cellular location | Nucleus (Probable): P45446 |
Total number of polymer chains | 2 |
Total formula weight | 29798.67 |
Authors | Stehlin-Gaon, C.,Willmann, D.,Sanglier, S.,Van Dorsselaer, A.,Renaud, J.-P.,Moras, D.,Schuele, R. (deposition date: 2003-01-21, release date: 2003-09-23, Last modification date: 2023-08-16) |
Primary citation | Stehlin-Gaon, C.,Willmann, D.,Zeyer, D.,Sanglier, S.,Van Dorsselaer, A.,Renaud, J.-P.,Moras, D.,Schuele, R. All-trans retinoic acid is a ligand for the orphan nuclear receptor RORbeta Nat.Struct.Biol., 10:820-825, 2003 Cited by PubMed: 12958591DOI: 10.1038/nsb979 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.5 Å) |
Structure validation
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